Strategies to tackle SARS-CoV-2 Mu, a newly classified variant of interest likely to resist currently available COVID-19 vaccines현재 사용 가능한 COVID-19 백신에 저항할 가능성이 있는 새로 분류된 관심 변종인 SARS-CoV-2 Mu에 대처하기 위한 전략Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration adopted approach B.1 lineage B.1.621 BNT161b2 booster dose Characteristics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine COVID-19 vaccine development Evidence exacerbated Genetic genomic Genomic surveillance global mass vaccination Health implementation infections Intervention Lineage mass vaccination Mu variant mutations Neutralizing non-pharmaceutical interventions (NPIs) NPIs potential risk public health measure public health measures Recombination reported required respiratory restrict SARS-CoV-2 SARS-CoV-2 B.1.621 SARS-CoV-2 virus sera shown Strains Strategy sub-lineage B.1.621.1 Surveillance survivor the SARS-CoV-2 virus therapeutic threat vaccination Vaccine vaccine breakthrough. Vaccine development variant variants [DOI] 10.1080/21645515.2022.2027197 PMC 바로가기 [Article Type] Article
A delayed resurgence of respiratory syncytial virus (RSV) during the COVID-19 pandemic: An unpredictable outbreak in a small proportion of children in the Southwest of Iran, April 2022Article Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory infections acute respiratory syndrome age caused changes in children circulation clinical information collected complete blood count coronavirus disease cough country COVID-19 COVID-19 outbreak COVID-19 pandemic described distribution emerging disease had no highlight hospital Hospitalization Hospitalized impacted Infection Influenza influenza virus influenza viruses Iran lockdown majority male medical condition Nasopharyngeal swab notable outbreak Outbreak. pandemic parameter pathogen Patient patients performed polymerase chain Precaution proportion Real-time PCR reported respiratory respiratory syncytial virus respiratory virus Result risk factor RSV SARS-CoV-2 subject tested threat Transmission viral genome virus virus [DOI] 10.1002/jmv.28065 PMC 바로가기
Cross-cultural comparison of nudging effects for environmental protection: A case-study of risk-averse attitudes toward disposable plasticsArticle Published on 2022-11-032022-11-16 Journal: PLoS ONE [Category] 비임상, [키워드] Analysis attribute benefit Canada caused conducted contributed correlated country COVID-19 cross-cultural Effect effect size effective Effects Factors identify IMPROVE individual information intervention effect Japan limit Linear regression model Machiavellianism positive attitude Randomized controlled trial risk significant effect suggested Support threat traits variety were measured [DOI] 10.1371/journal.pone.0277183 PMC 바로가기
Derivation, Functionalization of (S)-Goniothalamin from Goniothalamus wightii and Their Derivative Targets SARS-CoV-2 MPro, SPro, and RdRp: A Pharmacological PerspectiveArticle Published on 2022-10-172022-11-15 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] (S)-Goniothalamin Anti-viral anticancer antioxidant antiviral properties antiviral property approach characterization complex Compound coronavirus COVID-19 derivation derivative disease drug examined LC-MS molecular molecular dynamics MPro NMR pandemic performed phytochemical platform Pro RdRP required Research SARS-CoV-2 SARS-COV-2 infection Simulation study spike glycoprotein spike glycoprotein. target target protein threat [DOI] 10.3390/molecules27206962 PMC 바로가기
A Recombinant VSV-Based Bivalent Vaccine Effectively Protects against Both SARS-CoV-2 and Influenza A Virus InfectionArticle Published on 2022-09-282022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 신종인플루엔자, 진단, [키워드] Amino acid animal Bivalent bivalent vaccine C-terminal Cellular immune response conserved contagious COVID-19 Delta delta variant develop domain Ebola ectodomain Efficacy Evidence fused global public health glycoprotein H1N1 H3N2 hamster humoral immunization infections Infectious disease Influenza influenza A virus influenza virus influenza viruses M2 protein mice Neutralizing neutralizing antibody Point mutation PROTECT Protein provide recombinant reduced Respiratory disease respiratory droplet respiratory viral S2 domain SARS-CoV-2 SARS-CoV-2 Delta variant SARS-CoV-2 SP SARS-CoV-2 variant shown significantly Spike protein spike protein. the RBD threat transmitted Vaccine vaccine candidate vaccine platform variant vesicular stomatitis virus VSV VSV vector [DOI] 10.1128/jvi.01337-22 PMC 바로가기
Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome CoronavirusArticle Published on 2022-09-242022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 신약개발, 치료제, [키워드] acute diarrhea alpha-coronavirus Antiviral antiviral drug antiviral drugs approved drug block viral entry caused Compound coronavirus coronavirus disease COVID-19 deaths develop dose-dependent manner drug drug library Drug screening drug screening. drugs Epidemics exhibiting FIVE Infection inhibit inhibitory effect medication outbreak public health responsible resulting SADS-CoV SARS-CoV-2 Screening syndrome threat Vaccine viral replication virus viruses was performed zoonotic [DOI] 10.3390/ijms231911250 PMC 바로가기
Clinical trial and detection of SARS-CoV-2 by a commercial breath analysis test based on Terahertz technologyArticle Published on 2022-09-202022-11-15 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Algorithm Analysis Asymptomatic Brazil breath clinical Compound correlation COVID-19 diagnosing Diagnostic method evaluate gold standard Health Infection International Local National non-infected noninvasive organic Pandemics Patient Public Rapid required respiratory diseases RT-qPCR SARS-CoV-2 SARS-CoV-2 positivity screening method sensitivity social isolation specificity statistical tested the SARS-CoV-2 threat Trial virus [DOI] 10.1371/journal.pone.0273506 PMC 바로가기
A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 InfectionArticle Published on 2022-09-142022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 진단, [키워드] Affect antibody production B.1.1.529 B.1.1.7 lineage B.1.351 B.1.427 B.1.429 B.1.617.2 Beta coronavirus COVID-19 COVID-19 vaccine Delta delta variant demonstrated develop disease severity domain effective effective vaccine Effectiveness Efficacy elicited enhanced enhanced protection epitope Epsilon Gamma global public health highlight human ACE2 immunized immunized mice immunodominant IMPROVE Improved improved neutralizing activity induce Lineage mice mutant mutated Mutation Neutralizing Neutralizing activity neutralizing antibody Neutralizing antibody titer Numerous omicron Omicron and other variants Other P.1 pandemic Prevent probe protection Protective Protein pseudotyped pseudovirus RBD RBD protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants shown significantly Strains subunit Subunit vaccine. the receptor-binding domain threat Transmissibility Vaccine variant variants weight loss [DOI] 10.1128/jvi.00118-22 PMC 바로가기
COVID-19 preventive behavior among university students in Southeast Asia: Effects of knowledge, concern, awareness, and perceived riskArticle Published on 2022-09-092022-11-15 Journal: Frontiers in Public Health [Category] SARS, 치료기술, [키워드] age age and gender Analysis applied approach collected coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis Effect effective Factors fraction global health globe Infectious disease Interaction knowledge Malaysia measure MGA multiple group analysis pandemic Pandemics Partial Perceived risk Precaution preventive behavior. public health reduce retrieved risk significantly Spread study outcomes Surveillance threat Threats variables was performed [DOI] 10.3389/fpubh.2022.958021 PMC 바로가기
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinoloneResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료기술, 치료제, [키워드] A549 activity acute respiratory syndrome addition Analysis AUC binding binding affinity Bioinformatics analysis candidate caused Cell cell line clinical investigation Colon conducted coronavirus Coronavirus disease 2019 COVID-19 COVID-19 (Coronavirus disease 2019) COVID-19 infections dataset drug drug target effector memory Efficacy evaluated exhibited FIVE gene signature global pandemic human lung IC50 identification immune immunomodulation immunomodulatory immunosuppressive in vitro in vivo Inflammation Inflammatory Lungs peak plasma concentration pharmacokinetics positive-sense RNA virus respiratory infection SARS-CoV-2 SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) SARS-CoV-2 drug SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 pathogenesis SARS-CoV-2-infected patient suggested T cell therapeutic options therapeutic potential therapy threat transcriptomic translation translational vaccine candidates value [DOI] 10.1016/j.compbiomed.2022.105814 [Article Type] Research article